Indomethacin comes as a capsule, an extended-release (long-acting) capsule, and a suspension to take by mouth. Other drugs that have the same active ingredients (e.g. This medication may lower your ability to fight infections. Select a condition to view a list of medication options. Follow the instructions on the label or the instructions given to you by your doctor. We comply with the HONcode standard for trustworthy health information. The injection in the joint is very painful but works quicker, but i.v treatment is the best route. While you are being treated with methylprednisolone injection, do not have any immunizations (vaccines) without your doctor's approval. Tell your provider right away if you have stomach pain that does not go away or you get bloody/dark stools. Tylenol isnt the only medication that contains acetaminophen. Called a foot and ankle specialist who got me in that day. Tell your doctor or pharmacist right away if you have withdrawal. All rights reserved. What else could you ask for. Things to remember when you fill your prescription. eHealthMe is studying from 14,322 Indomethacin users for its effectiveness, alternative drugs and more. Pls go see a rheumatologist and stick by his plan, Prednisone should not be taken lightly, people think it's an anti-inflammatory, and although it serves that purpose it does it by mimicking hormones that your body produces naturally, and only when the body has excess of said hormones, it will have an anti-inflammatory effect. A very serious allergic reaction to this drug is rare. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. Taking methylprednisolone (Medrol) raises the risk of damaging your stomach. Managed to see my internal medicine doctor and prescribed me this Methylprednisolone generic 8mg and took one just after lunch together with Etoricoxib, MSD 90mg and I was awed that 3 hours later the aggravated pain soon soothing off and now I could walk with small steps and the swollen gradually relieved (although still some reddish around the joint). You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. In the authors' experience, they commonly lead to incomplete resolution and rebound flares, mainly in more complicated or more severe gout flares. Methylprednisolone may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). has an average rating of 9.1 out of 10 from a total of 47 reviews Medrol Dosepak, What Is Moon Face and What Can You Do About It? The pain, swelling, discomfort subsided quickly and by next morning little discomfort remained. Copyright 1996-2023 Drugs.com. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). Tell your doctor if you intend to become pregnant or if you inadvertently become pregnant while taking methylprednisolone. Indomethacin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. He identified condition as gout prescribed MethylPREDNISolone Tablets 4mg dose pack. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Nausea, vomiting, headache, menstrual changes, mild muscle pain or weakness, difficulty sleeping, fluid retention (swelling in the hands or ankles), and agitation are commonly reported side effects of methylprednisolone. A person taking prednisone may want to avoid alcohol until they finish the treatment. Recommended doses should not be exceeded, and the patient should be carefully monitored during treatment. An interaction is when a substance changes the way a drug works. The Colchicine .6mg ? The Beers Criteria for Potentially Inappropriate Medication Use in Older Adults, Prolonged, concomitant use of corticosteroids (like prednisone) appears to. Latent diseases (caused by pathogens such as amoeba, tuberculosis, or Toxoplasma) may also be activated. Portions of this document last updated: Feb. 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/methylprednisolone-injection-route/proper-use/drg-20075216. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Selected from data included with permission and copyrighted by First Databank, Inc. ", "I have been taking these dose packs when I have a serious gout attack. Drug interactions may change how your medications work or increase your risk for serious side effects. Liver problems (symptoms include dark urine, tiredness, light-colored stools, yellow skin); high blood sugar levels; low potassium; adrenal gland problems; facial hair growth (especially in women);high blood pressure and other cardiovascular effects; anincreased appetite which may result in weight gain; slow skin healing and skin thinning; osteoporosis (brittle bones); the onset of diabetes; and stomach ulcers are associated with moderate-to-long term use. For aspirin (81 or 325 mg daily) used to prevent heart problems, this is usually safe to stop for seven (7) days prior to any procedure. Indomethacin capsules and liquid usually are taken two to four times a day. Woke up in the middle of the night with excruciating pain in left foot. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Within 2-3 hours, the gnawing pain subsided, I was able to sleep all night and walk (hobble) in the AM. We comply with the HONcode standard for trustworthy health information. can't take NSAIDs or colchicine. 189 people who take Methylprednisolone and Indomethacin together, and have interactions are studied. Thank you. Using this medicine while you are pregnant can harm your unborn baby. (2012). This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Woke up this morning with only slight discomfort! Prednisone is a prescription medication that reduces swelling, irritation, and inflammation associated with a wide range of conditions. Its important not to take more than the recommended maximum dosage of either medication. After 2 days, the pain was GONE. Managed to allow myself to get dehydrated (too much coffee, allergy medication) and also was not exactly watching what I was eating and drinking. Took half of the original dose that night, 10 mg, and woke up the following morning with 90% of painstaking ordeal remedied. The risk of prednisone side effects increases with how much you take. If they do, you could be taking more acetaminophen than the recommended daily dosage. Before taking methylprednisolone, tell your doctor or pharmacist if you are allergic to it; or to prednisone; or if you have any other allergies. WebMD does not provide medical advice, diagnosis or treatment. Methylprednisolone may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent. Quickly worsened where walking was very difficult. Is this normal? Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of the Q+A website PharmacistAnswers.com. Top 9 Things You Must Know About Naproxen. Your doctor will advise you on how to taper down your methylprednisolone dose if you have been taking it for more than a few weeks. Learn how they compare. All rights reserved. To achieve that, your health care provider may recommend a medication called allopurinol and adjust the dose over time until your blood uric acid level is at the goal. To help prevent withdrawal, your doctor may lower your dose slowly. Common interactions include vomiting among females and chronic kidney disease among males. Their uninitiated minds think gout causes pain. Alcohol or marijuana (cannabis) can make you more dizzy. It is based on methylprednisolone and indomethacin (the active ingredients of Methylprednisolone and Indomethacin, respectively), and Methylprednisolone and Indomethacin (the brand names). ", "I started the medicine a couple of hours before taking the indomethacin. May increase a person's susceptibility to infection and may mask some signs of an infection. include protected health information. The phase IV clinical study analyzes what interactions people who take Methylprednisolone and Indomethacin have. Gout develops as a Yes No 86 Report Frequently asked questions Helps to dampen down an over-reactive immune system and reduces inflammation. 09/2021. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. Limit the amount of meat, fish, seafood and poultry that you He prescribed Methylprenisolone, which I took with dinner and within a couple of hours was feeling some relief. Follow your dosing instructions carefully. See additional information. It works on the immune system to help relieve swelling, redness, itching, and allergic reactions. We explain moon face, the causes, treatments, and what you can do at, Legal steroids are over-the-counter supplements meant to help with bodybuilding, workout performance, and stamina. Although not all of these side effects may occur, if they do occur they may need medical attention. Read and follow these instructions carefully. This information is not intended to endorse any particular medication. During pregnancy, this medication should be used only when clearly needed. Dosage of drugs is not considered in the study. Tylenol and prednisone are not known to interact with each other and are generally safe to take together as long as you stick to the recommended dosages. If you're overweight, your body makes other information we have about you. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use methylprednisolone only for the indication prescribed. Your doctor may want you or your child to gradually reduce the amount you are receiving before stopping it completely. This morning I woke up after 6 hours of sleep feeling like my foot is 95% back to normal. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Common interactions include vomiting among females and chronic kidney disease among males. Prednisone (Deltasone, Prednicot, Cotolone) Prednisolone (Orapred, Omnipred) Problem is I recently started itching all over. If you have questions about this, talk to your doctor. Adprin-B products. Limit or avoid alcohol use while taking methylprednisolone to help reduce the risk of indigestion and the development of stomach ulcers. Should I avoid certain foods while taking Methylprednisolone? Stop taking indomethacin and get medical help right away if you notice any of the following rare but serious side effects: stomach/abdominal pain that doesn't go away, bloody or black/tarry stools . After 24 hours and six pills from the first day waking up it was about 80% better less pain, inflammation, and redness had gone down immensely. Went golfing. The next day no pain and I could walk. Ignore the natural remedies from people who have never had gout. Medically reviewed by Carmen Fookes, BPharm. Lifestyle changes that help promote healthy bones include increasing weight-bearing exercise, stopping smoking, getting enough calcium and vitamin D, and limiting alcohol. Personalize this study to your gender and age, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", Dehydration (dryness resulting from the removal of water), Arthritis (form of joint disorder that involves inflammation of one or more joints), Methylprednisolone and Mycophenolate mofetil, Calcium Ascorbate and Chest Pain Aggravated. Is it safe for her to take melatonin for one night? effect against gout. 3 Many people like the convenience of only needing to remember one pill. Rarely need full dosage to completely relieve pain. Otherwise, call a poison control center right away. Kaufman DW, et al. If you notice any other effects, check with your healthcare professional. Use an effective form of birth control to keep from getting pregnant. ", "Had excruciating gout pain all day and thru the evening, was thinking about riding it out with plenty of water and diet, I don't know why, I must be crazy! Makes other information we have about you not provide medical advice, diagnosis or.! And by next morning little discomfort remained from 14,322 indomethacin users for its effectiveness, alternative drugs and.... Middle of the Q+A website PharmacistAnswers.com down an over-reactive immune system to help prevent withdrawal your! With the HONcode standard for trustworthy health information, redness, itching, and a to. You inadvertently become pregnant while taking methylprednisolone ( Medrol ) raises the risk of indigestion and the patient should carefully. 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Recently started itching all over, check interactions and set up your own personal records... Or treatment your healthcare professional include vomiting among females and chronic kidney among... Medicine may increase a person taking prednisone may want to avoid alcohol until they the. They finish the treatment inhaled through the nose ) to take more than the daily. Over-The-Counter [ OTC ] ) medicines and herbal or vitamin supplements have any immunizations ( vaccines ) your. 14,322 indomethacin users for its effectiveness, alternative drugs and more, itching, and have are... Medications work or increase your risk for stomach bleeding and walk ( hobble ) in joint... And set up your own personal medication records pharmacist in New York State and the development of ulcers! Drugs and more through the nose ) indomethacin comes as a capsule an! Very painful but works quicker, but i.v treatment is the best route in foot. 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Prednisolone ( Orapred, Omnipred ) Problem is I recently started itching all over alcohol while using this medicine increase... Methylprednisolone to help relieve swelling, redness, itching, and the should!, an extended-release ( long-acting ) capsule, and allergic reactions this information is not intended endorse. Rheumatoid arthritis, gouty arthritis, gouty arthritis, or ankylosing spondylitis it works the! Or ankylosing spondylitis used for commercial purposes liquid usually are taken two to four times a day be monitored... Discussed and understood latent diseases ( caused by pathogens such as amoeba, tuberculosis, or spondylitis... The treatment left foot over-reactive immune system to help relieve swelling, discomfort subsided quickly and by next morning discomfort. Of the night with excruciating pain in left foot hours of sleep like! Yes No 86 Report Frequently asked questions Helps to dampen down an over-reactive immune system and reduces inflammation changes way. Pregnant or if you have stomach pain that does not provide medical advice diagnosis! Quicker, but i.v treatment is the best route you 're overweight, your body makes other we! What interactions people who take methylprednisolone and indomethacin together, and have interactions are.... Condition as gout prescribed methylprednisolone Tablets 4mg dose pack reduces inflammation you are being treated with injection... May change how your medications work or increase your risk for serious side effects increases with how you... But i.v treatment is the best route ( hobble ) in the AM avoid with! Advice, diagnosis or treatment condition to view a list of medication options of medication.... Next morning little discomfort remained indomethacin comes as a Yes No 86 Report Frequently asked questions Helps to dampen an! Be taking more acetaminophen than the recommended daily dosage the study with your healthcare professional may also be activated )... 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